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1. Access to Vascular
A vascular sheath is inserted after a little incision is made in the groin (usually the femoral artery) or occasionally the wrist. This allows a catheter to be inserted into the artery system.
IV Thrombolysis
IV Thrombolysis
procedure steps
2. Getting to the Clot
A microcatheter is carefully inserted by guidewire into the cerebral arteries using fluoroscopic (X-ray) imaging, all the way to the precise location of the thrombus (clot) inside the brain channel. To prevent vascular damage, precise navigation is essential.
3. Setting Up the Microcatheter
Gentle angiography is used to identify the position and extent of the blockage once the microcatheter tip has been verified at the clot site.
4. Thrombolytic Agent Administration
Via the microcatheter, thrombolytic drugs (such urokinase or alteplase) are gradually injected into the thrombus or very close to it. Clot burden, location, and patient-specific parameters affect the infusion rate and total dose. Dissolving the clot and restoring flow are the objectives.
5. Tracking Lysis and Procedure Development
To evaluate clot breakdown and artery reopening, periodic angiograms and/or continuous fluoroscopic monitoring are performed. The catheter may be repositioned to optimize lysis if needed. Depending on the size and reaction of the clot, the process could take minutes to hours.
disease treated
Ischemic Stroke
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Cerebral/venous Sinus Thrombosis
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May-thurner Syndrome
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suitable for
Patients with Acute Ischemic Stroke
Acute ischemic stroke patients experience neurological symptoms as a result of a clot obstructing blood flow to brain tissue.
During a Particular Time Period
It should ideally be completed within 4.5 hours of the onset of symptoms, but depending on sophisticated brain imaging, it may take up to 9 hours or longer in certain situations.
Different Sizes of Vessel Occlusions
It is possible to treat clots in both minor arteries and major vessels (such the MCA and ICA).
When Quick Reperfusion Is Required
used as a first-line therapy to break up clots and restore blood flow, particularly in cases when mechanical thrombectomy is not recommended, is not available, or is used as an adjuvant.
benefits
Quick Clot Dissolution and Reperfusion
In order to minimize brain tissue damage, IV thrombolysis stimulates the body’s fibrinolytic system to swiftly dissolve the clot and restore blood flow to the afflicted brain region.
Better Functional Outcomes
Compared to patients who do not receive treatment, those who receive IV thrombolysis during the treatment window are substantially more likely to experience little to no disability three months after their stroke.
Extended Therapy Windows
Treatment for wake-up strokes or up to nine hours after onset is now possible thanks to advancements in imaging, which increases the number of patients who can benefit.
Complement to Mechanical Thrombectomy
IV thrombolysis improves recanalization rates and results in major artery occlusions by acting as a bridge or adjunct to thrombectomy.
Potential to Treat a Wide Range of Stroke individuals
IV therapy is minimally intrusive and can be administered to individuals with mild to severe stroke and a variety of vascular occlusions.
Better Survival and Decreased Disability
According to meta-analyses, patients receiving thrombolysis have significantly lower death or dependence rates at three to six months.
Accessible Early Treatment Option
Stressing the crucial “time is brain” principle, it can be quickly provided in emergency or pre-hospital settings (such as mobile stroke units).
post-treatment recovery
Monitoring and Follow-Up Scans
Frequent brain imaging (CT or MRI) within a day to measure brain repair, identify hemorrhagic change, and gauge reperfusion.
ongoing observation for any consequences or worsening of the neurological condition.
Medication or Blood Thinners
Antiplatelet medications, such as aspirin, are given to stop new clots after 24 hours and confirmation of no bleeding.
Medication schedules must be strictly followed.
Rehabilitation and Physiotherapy
Long-term recovery and functional independence are enhanced by the early beginning of customized rehabilitation that focuses on mobility, speech, coordination, and strength.
Changes in Lifestyle
Manage your blood pressure, diabetes, and cholesterol. Reducing alcohol consumption and quitting smoking both lower the chance of another stroke.
Hydration and Diet
Keep up a heart-healthy, well-balanced diet that is low in salt and full of fruits and vegetables.
Drinking enough water promotes general health when recovering.
Mental and Emotional Assistance
Psychological adjustment is a part of stroke rehabilitation; early mental health therapies, support groups, and counseling all help.
Frequent Check-Ups
