Deep Vein Thrombosis
Deep Vein Thrombosis
WHAT IS
DEEP VEIN THROMBOSIS (DVT)?
A blood clot that forms in a deep vein, usually in the leg, causes deep vein thrombosis (DVT), which manifests as pain, swelling, redness, and warmth. If the clot spreads to the lungs, DVT can result in dangerous side effects like pulmonary embolism. Anticoagulants and occasionally catheter-based removal are the mainstays of prevention and treatment.
causes
Prolonged immobility
Injury or surgery
Hormonal factors
Obesity
Smoking
Serious medical conditions
inherited blood clotting
Advanced age
family history
intravenous drug use
Inflammation
High cholesterol
symptoms
Swelling in one leg, sometimes both
Pain or tenderness
Warmth in the affected area
bluish discoloration of the skin over the affected vein
Skin that feels tight or stretched near the swollen area
Visible or enlarged veins that feel hard or sore
Pain that worsens when standing or walking
if untreated?
Pulmonary Embolism (PE)

A life-threatening condition where a clot breaks free and blocks blood flow to the lungs.
Post-Thrombotic Syndrome (PTS)

Chronic pain, swelling, skin discoloration, and ulcers caused by vein damage from the clot.
Chronic Venous Insufficiency

Poor blood flow through veins leading to persistent leg swelling and skin changes.
Recurrent DVT

Increased risk of developing another blood clot.
Venous Gangrene

Rare but severe tissue death due to blocked blood flow, potentially leading to amputation.
Diagnosis
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Physical Examination
-
The healthcare provider checks for swelling, tenderness, and skin color changes in the leg.
D-dimer Blood Test
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Measures a substance released when blood clots dissolve. A high level suggests the possibility of a clot but is not specific to DVT alone.
Duplex Ultrasound
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The standard and most commonly used test. It uses sound waves to create images of blood flow and detect clots. If the vein cannot be compressed by pressure from the ultrasound probe, it likely contains a thrombus.
Venography
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An invasive test where dye is injected into a vein and X-rays are taken to visualize clots. It is rarely used now due to the efficacy of ultrasound.
Magnetic Resonance Imaging (MRI)
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Sometimes used to detect DVT in areas difficult to assess with ultrasound, like the pelvis or abdomen.
Computed Tomography (CT) Venography
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Used in specific cases to visualize deep veins and clots.
