Dr. Jenny Gandhi

WHAT IS
CEREBRAL/VENOUS SINUS THROMBOSIS?

A blood clot in the brain’s venous sinuses that stops blood from draining out. This can lead to headaches, neurological problems, and even seizures or events that look like strokes. Serious problems can be avoided by starting treatment right away with anticoagulants.

causes

Pregnancy and the postpartum period
Use of oral contraceptives
Inherited or acquired thrombophilia
Recent head trauma or neurosurgery
Infections near the brain
Cancer or malignancy
Chronic inflammatory
Dehydration
Obesity
Hematologic disorders

symptoms

Severe, persistent headache
Seizures, often focal but sometimes generalized
Weakness or numbness affecting one or both sides of the body
Difficulty speaking or understanding language
Visual disturbances like blurred or double vision
Nausea and vomiting
Altered mental status, confusion, or decreased consciousness
Swelling of the optic nerve causing visual problems
coma or neurological deficits similar to stroke

if untreated?

Brain swelling (cerebral edema) and increased intracranial pressure
Venous infarction (tissue damage) and brain hemorrhage
Seizures
Permanent neurological deficits (weakness, paralysis, vision loss)
Coma or rapid decline in consciousness
Stroke
Pulmonary embolism
Chronic headaches and cognitive impairment
Residual epilepsy or recurrent thrombosis
Development of dural arteriovenous fistula
Death

diagnosis

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MRI with MR Venography
  • The most sensitive and widely used test to see blood clots and lack of blood flow in the sinuses or cerebral veins is MRI with MR Venography.
CT with CT Venography
  • Particularly helpful in emergency situations, CT with CT Venography can quickly identify venous thrombosis and related brain abnormalities.
Digital Subtraction Angiography (DSA)
  • When endovascular intervention is planned or other imaging is inconclusive, digital subtraction angiography (DSA) may be considered.
Blood tests
  • Used to look for risk factors or underlying clotting disorders.

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